Diagnostic utility of the Millon Adolescent Clinical Inventory (MACI) with depressive disorders

Donna Elise Murphy (2000)

This archival study examined the diagnostic utility of the Millon Adolescent Clinical Inventory (MACI) for depressive disorders with and without comorbid disruptive behavior disorders. Diagnostic, classification rates (sensitivity, specificity, positive predictive power, negative predictive power, and overall predictive power) were determined based on MACI print out diagnoses and depressive scale cutoff scores as compared to primary and provisional DSM-IV diagnoses given upon hospital admission. Overall, the MACI produced diagnostic classification rates (.42-.91) in the range of other adolescent self-report measures; however, the depressive group produced better rates than the comorbid group. Notably, the depressive group produced positive predictive power rates ranging from 82% to 91%. The Depressive Affect scale demonstrated better diagnostic classification rates than the Doleful Personality scale. Finally, the depressive group and comorbid group produced significantly different scale elevations, such that, scales 1, 2A, 3, and E were higher for the depressive group while scales 6A, 6B, F, G, BB, CC, and DD were higher for the comorbid group. In sum, study results found significant support for the diagnostic utility of the MACI with the depressive group; however, diagnostic utility with the comorbid group was not well supported. Recommendations for future studies include a comparison based on diagnoses established with a structured clinical interview, a larger sample from diverse clinical settings, and regression analyses on the scales.